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报告1980年至1996年10月手术治疗31例重症肌无力合并胸腺瘤的结果。31例占同期手术治疗120例重症肌无力之25.8%。按Masaoka分期属I期7例,I期8例,II期15例,IV期1例,术后15例发生危象,均采用气管切开及辅助呼吸,1例死于危象。随访半年至8年,平均37个月,5年内死亡6例,其中II期4例,I期2例。结论:重症肌无力合并胸腺瘤术后危象的发生率远较未合并胸腺瘤者高,及时气管切开行辅助呼吸是处理的关键;胸腺瘤的Masaoka病理分期与预后明显相关,肌无力的严重程度对预后亦有重要影响
Reported 31 cases of myasthenia gravis combined with thymoma surgery from 1980 to October 1996. Thirty-one patients accounted for 25.8% of 120 cases of myasthenia gravis during the same period of operation. According to Masaoka stage, there were 7 cases of stage I, 8 cases of stage I, 15 cases of stage II, and 1 case of stage IV. A crisis occurred in 15 cases. Tracheotomy and assisted respiration were used. One case died of a crisis. Follow-up from six months to eight years, with an average of 37 months, 6 cases died within 5 years, including 4 cases of stage II and 2 cases of stage I. Conclusion: The incidence of postoperative crisis of myasthenia gravis combined with thymoma is much higher than that of patients without thymoma. Prompt tracheotomy for assisted respiration is the key to treatment. The Masaoka pathological stage of thymoma is significantly associated with prognosis, and myasthenic Severity has an important effect on prognosis