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本研究报导抗人肝癌单克隆抗体ＨＡｂ１８与载阿霉素（ＡＤＲ）的白蛋白毫微粒（ＡＤＲ－ＨＳＡ－ＮＰ）共价交联的免疫毫微粒（ＨＡｂ１８－ＡＤＲ－ＨＳＡ－ＮＰ）的制备及其体外靶向结合和杀伤肝癌细胞的特性。１材料和方法１．１ ＨＡｂ１８－ＡＤＲ－ＨＳＡ－ＮＰ的制备
The present study reports the preparation of immunosensor nanoparticles (HAb18-ADR-HSA-NP) covalently cross-linked with anti-human hepatoma monoclonal antibody HAb18 and ADR-loaded albumin nanoparticles (ADR-HSA- It targets in vitro the characteristics of binding and killing hepatoma cells. 1 Materials and methods 1.1 Preparation of HAb18-ADR-HSA-NP