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活化型表皮生长因子受体（EGFR）指磷酸化后的表皮生长因子受体，是一种相对分子质量为１７００００、具有生物学活性的跨膜糖蛋白。其广泛分布于哺乳动物细胞膜上，直接参与细胞的信号转导，促进细胞的增殖和分化；E２F是一种细胞周期依赖性转录调节因子，它存在于细胞核内，
Activated Epidermal Growth Factor Receptor (EGFR) is a phosphorylated epidermal growth factor receptor that is a biologically active transmembrane glycoprotein with a molecular weight of 170,000. It is widely distributed in the mammalian cell membrane, directly involved in cell signaling and promote cell proliferation and differentiation; E2F is a cell cycle-dependent transcription regulator, which exists in the nucleus,