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作者分析了处于完全缓解的93例急淋儿童,随机予以3种不同方法的中枢神经系统(CNS)预防后进行头部 CT 扫描的结果。Ⅰ组:29例接受氨甲喋呤鞘内注射(IT MTX),每次12mg/m~2,共6次;Ⅱ组:30例接受Ⅰ组同样治疗外,另加2400拉德头颅照射(CRT),分12次给予;Ⅲ组:其余34例除同Ⅰ组外,另加 MTX500mg/m~2静脉24小时滴注,每3周1次,共3次。扫描异常总发病率为35%,其中91%只有轻微异常,2.1%(2例)属于中度异常,1.1%(1例)属于显著异常。以上3组 CT 扫描异常率分别为30%、40%和35%,这些差异缺乏统计学意义。本研究突出的发现是,在任何一个治疗组中所见的显著异常发病率很低,虽然,总的异常发病率为35%,但是,其中绝大多数只有轻微的变化,通常包
The authors analyzed 93 children with acute erectile dysfunction who were randomized to receive head CT scans after three different methods of CNS prophylaxis. In group Ⅰ, 29 patients received methotrexate intrathecal injection (IT MTX) of 12 mg / m 2 each for 6 times. Group Ⅱ: 30 patients received the same treatment of group Ⅰ plus 2400 rad head acuity (CRT) Divided into 12 times; Group Ⅲ: the remaining 34 cases except the same group Ⅰ, plus MTX500mg / m ~ 2 intravenous infusion of 24 hours, once every 3 weeks, a total of 3 times. The overall incidence of abnormal scanning was 35%, of which 91% had only minor abnormalities, 2.1% (2 cases) were moderately abnormal, and 1.1% (1 case) were significant abnormalities. The above three groups of CT scan abnormalities were 30%, 40% and 35%, these differences lack of statistical significance. The prominent finding of this study was that the incidence of significant abnormalities seen in any of the treatment groups was low, although the overall incidence of abnormalities was 35%, but the vast majority of them had only minor changes,