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目的：分析咪唑斯汀治疗荨麻疹并发过敏性鼻炎的临床疗效。方法选取2013年3月~2014年8月在我院就诊的75例荨麻疹并发过敏性鼻炎患者，按照治疗方式分为治疗组(40例)和对照组(35例)，治疗组采取咪唑斯汀治疗，对照组采取西替利嗪治疗，对比两组的治疗效果。结果治疗组的临床治疗总有效率为90.0%，显著高于对照组的74.3%(P<0.05)。治疗后，治疗组荨麻疹、过敏性鼻炎症状评分显著低于对照组，荨麻疹、过敏性鼻炎症状改善起效时间显著短于对照组(P0.05)，但治疗组的复发率高于对照组(P<0.05)。结论咪唑斯汀治疗荨麻疹并发过敏性鼻炎的效果显著，具有较高的治疗安全性。“,”Objective To analysis the clinical effect of mizolastine in treatment of urticaria and allergic rhinitis. Meth-ods 75 patients with urticaria and allergic rhinitis in our hospital from March 2013 to August 2014 were selected.They-were divided into treatment group (n=40) and control group (n=35) according to different therapy measures.The treat-ment group was given mizolastine,the control was given cetirizine.The therapy effect was compared between two groups. Results The total efficient rate in treatment group was 90.0%,which was higher than 74.3%of control group(P<0.05).Af-ter treatment,the symptom scores of urticaria and allergic rhinitis in treatment group were significantly lower than those of control group,urticaria and allergic rhinitis symptoms improved onset time in treatment group were significantly short-er than those of control group(P0.05),but the difference of recurrence in two groups was significant (P<0.05). Conclusion Mizolastine has significant effect in treating urticaria and allergic rhinitis, and has higher security.