胰腺或邻近部位的肿瘤局部侵犯包绕肠系膜上动脉时，联合血管切除与重建的根治性手术仍然是唯一可能治愈的手段。然而，肠系膜上动脉直接切除原位重建对技术的要求较高，术后并发症发生率和病死率高。近年来，自体小肠移植技术的诞生为解决这一临床难题提供了一种新的思路。该技术融合了器官离体保存技术和小肠移植技术，首先将肿瘤及受累器官整块游离、切除、移出体内，并于体外快速灌洗，低温保存后在工作台清除病灶，最后将正常小肠移植回体内进行血管吻合和消化道重建修复。这一技术突破了肿瘤包绕肠系膜上动脉时不能切除的手术禁区，在实现肿瘤根治性切除的同时，最大程度保留了小肠结构的完整性和消化吸收功能，但手术的复杂性、高风险性和术后并发症在很大程度上制约着该项技术在临床上推广应用。“,”When abdominal neoplasms originating from the pancreas or nearby organs locally involving the superior mesenteric artery (SMA), complete resection is still the only hope for cure. However, SMA resection and reconstruction is a complex surgical procedure associated with high postoperative morbidity and mortality. Intestinal autotransplantation has recently emerged in clinical practice as a treatment option for selected patients with neoplasms involving the SMA. The original procedure involved n en bloc removal of a tumor together with the intestine, n ex vivo resection and reconstruction of gastrointestinal tract by an intestinal autograft. To further refine this complex procedure, a modified method was developed in which a segmental bowel autograft is selected and harvested first during the initial stage of the operation, and radical resection of the neoplasm is carried out thereafter. The modification would better protect a healthy bowel autograft from potential damage due to prolonged warm ischemia and allow the subsequent lengthy process of dissection to be performed in an unrushed manner. Furthermore, this alteration would better adhere to the general principles of minimal tumor manipulation during operation and potentially decrease the risks of tumor implantation during n in vitro organ perfusion. Although intestinal autotransplantation has expanded eligibility for resection of otherwise unresectable lesions involving the SMA, its operative complexity, high risks, and post-operative complications largely limit its clinical applications.n