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慢性气管炎病人常因不易咳出痰液,引起一系列症状,甚至造成严重后果。因此寻找高效、速效、长效的消炎药及祛痰药十分迫切。有关排除痰液的实验研究,一般多采用反映动物气管分泌量的方法来间接判断药物的疗效;我们试用了测定气管纤毛-粘液运送速度的方法,试图找出能反映“排痰”及呼吸道清除异物功能的指标,以寻找、选择有“祛痰”作用并能增强呼吸道局部防御功能的中草药,为今后疗效鉴定和“扶正培本”等方面的研究提供线索。
Patients with chronic bronchitis are often unable to cough up sputum, causing a series of symptoms, and even causing serious consequences. Therefore, it is very urgent to find effective, quick-acting, long-acting anti-inflammatory drugs and expectorants. In the experimental study on the elimination of sputum, the method of reflecting the secretion of trachea in animals is often used to indirectly judge the efficacy of the drug; we have tried to determine the way of tracheal cilia-mucus transport speed, trying to find out that it can reflect the “efflux” and respiratory clearance. The index of foreign body function is to search for and select Chinese herbal medicines that have a “cockroach” effect and can enhance the local defense function of the respiratory tract. This will provide clues for the future efficacy evaluation and research on “supporting the right posture.”