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目的 通过对本组手术方法和入路的探讨,旨在提高嗅神经母细胞瘤的手术疗效。方法 4例嗅神经母细胞瘤患者均先由耳鼻喉科经鼻旁切口入路切除鼻腔及副鼻窦内肿瘤,接着由神经外科医生经改良翼点入路行开颅肿瘤切除及颅底重建。结果 本组4例无手术死亡,其中肿瘤全切除3例,次全切除1例(副鼻窦内残存)。随访3年,3例存活,1例术后死于急性脑梗塞。结论 神经外科、耳鼻喉科联合经鼻旁—改良冀点入路切除嗅神经母细胞瘤是首选治疗手段,术后辅以放疗有预防复发作用。
Objective Through this group of surgical methods and approaches to explore, to improve the surgical efficacy of olfactory neuroblastoma. Methods Four patients with olfactory neuroblastoma were treated with transnasal incision of otolaryngology and nasal and paranasal sinuses. Neurosurgical surgeons performed craniotomy and skull base reconstruction with modified pterional approach. Results The group of 4 patients died without surgery, including tumor resection in 3 cases, subtotal resection in 1 case (paranasal sinus remnants). Three years follow-up, 3 patients survived, 1 patient died of acute cerebral infarction. Conclusion Neurosurgery, otolaryngology combined with transnasal - modified Ji point point excision of olfactory neuroblastoma is the first choice of treatment, adjuvant radiotherapy postoperative recurrence.