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目的探讨氨甲蝶呤(MTX)单次肌肉注射治疗输卵管妊娠的临床疗效。方法对我院2008年11月至2010年11月收治的39例输卵管妊娠患者应用MTX 50 mg/m2单次肌肉注射,用药后观察患者的一般情况,定时监测血β-绒毛膜促性腺激素水平及B超检查,同时记录MTX的不良反应情况。结果本组患者治愈32例,治愈率为82.1%,失败7例,占17.9%,大多数患者无明显不良反应。结论氨甲蝶呤单次肌肉注射治疗输卵管妊娠的疗效显著,方法简便,安全可靠,是临床上保守治疗输卵管妊娠的理想方法,值得临床上推广。
Objective To investigate the clinical efficacy of methotrexate (MTX) single intramuscular injection in the treatment of tubal pregnancy. Methods Thirty-nine patients with tubal pregnancy who were treated in our hospital from November 2008 to November 2010 were injected intramuscularly with MTX 50 mg / m2. The general condition of the patients was observed after treatment. The level of serum β-HCG And B-ultrasound, while recording the adverse reactions of MTX. Results The patients were cured in 32 cases, the cure rate was 82.1%, failure in 7 cases, accounting for 17.9%, most patients without significant adverse reactions. Conclusion A single intramuscular injection of methotrexate for the treatment of tubal pregnancy has significant curative effect. The method is simple, safe and reliable, and it is an ideal method for the conservative treatment of tubal pregnancy clinically. It is worth to be popularized clinically.