已有报道槲皮素能显著抑制促癌剂的作用、抑制离体恶性细胞的生长、抑制艾氏腹水癌细胞DNA、RNA和蛋白质的合成、诱发艾氏腹水癌细胞cAMP的增多。 本文用[~3H]胸苷参入小白鼠白血病L7712细胞DNA作为指标,测出槲皮素对DNA合成的半抑制浓度为33.4μg/ml。用Painter方测槲皮素对DNA合成速率的后作用表明即使把槲皮素从细胞培养液中清除后1—3 h, It has been reported that quercetin can significantly inhibit the action of cancer promoters, inhibit the growth of isolated malignant cells, inhibit the synthesis of DNA, RNA and protein of Ehrlich ascites carcinoma cells, and induce the increase of cAMP in Ehrlich ascites carcinoma cells. In this paper, we used [~3H]thymidine incorporation into DNA of mouse leukemia L7712 cells as an index to determine the semi-inhibitory concentration of quercetin to DNA synthesis of 33.4 μg/ml. Using Painter’s method, the subsequent effect of quercetin on DNA synthesis rate showed that even if quercetin was removed from the cell culture fluid for 1-3 h,