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近年来抗EB病毒壳抗原的免疫球蛋白A抗体(VcA-IgA)的检测已被广泛地采用为鼻咽癌的辅助诊断。血清学的动态检测还发现,VcA-IgA抗体滴度随病程的进展和肿瘤转移而升高;随放疗后患者存活期的延长而渐趋下降;一旦复发,抗体滴度又回复上升至疗前水平。因此,VcA-IgA抗体水平的动态变化在一定程度上可以反映鼻咽癌患者的病情变化与疗效。本文报告我们对56例经深部X线治疗的鼻咽癌患者血清中抗VcA-IgA抗体的近期观察结果。 材料与方法:血清标本采自中山县人民医院,随机采集56例经病理确诊的鼻咽癌患者的疗前,深部X线治疗期中(即第二段放疗开始)与疗后一个月的血
In recent years, the detection of immunoglobulin A antibody (VcA-IgA) against EBV antigen has been widely used as an auxiliary diagnosis of nasopharyngeal carcinoma. The serological detection also found that the antibody titer of VcA-IgA increased with the progression of disease and tumor metastasis, decreased gradually with the survival of patients after radiotherapy, and once recurred, the antibody titer rose back to pretreatment. Level. Therefore, the dynamic changes of VcA-IgA antibody level can reflect the changes and efficacy of NPC patients to some extent. This article reports our recent observations of serum anti-VcA-IgA antibodies in 56 patients with nasopharyngeal carcinoma treated with deep X-rays. Materials and Methods: Serum samples were collected from People’s Hospital of Zhongshan County and 56 patients with nasopharyngeal carcinoma diagnosed by pathology were randomly collected before treatment, during deep X-ray treatment period (ie, the second stage of radiotherapy started) and one month after treatment.