论文部分内容阅读
目的:了解新疆生产建设兵团麻疹流行高峰后全人群的抗体水平,为制定防治策略提供依据。方法:2008年麻疹流行高峰年后,根据地理位置和人群年龄在全兵团分层随机抽取有效血样1415人份;并采用酶联免疫吸附试验检测麻疹IgG抗体。结果兵团麻疹流行年后人群麻疹抗体平均阳性率为85.5%,几何平均浓度(GMC)为819mIU/ml;15岁以下小年龄人群平均阳性率为84.0%,GMC为823 mIU/ml。15岁以上成人麻疹抗体平均阳性率为87.9%,GMC为811 mIU/ml。其中2岁以下和15～34岁人群抗体水平相对较低。不同年龄组、不同地区、流动人口和常住人口的麻疹抗体阳性率和GMC差异均显著;不同性别和不同民族间无显著性差异。结论:2岁以下和15～34岁的人群是麻疹发病的高发人群;南疆部分偏远地区和流动人口的基础免疫存在薄弱环节。兵团麻疹控制应重点关注此类重点人群。
OBJECTIVE: To understand the antibody level of whole population after the peak of measles epidemics in Xinjiang Production and Construction Corps, and to provide the basis for making prevention and treatment strategies. Methods: After the peak of measles epidemic in 2008, 1415 valid blood samples were randomly selected according to the geographical position and the age of the population. The measles IgG antibody was detected by enzyme - linked immunosorbent assay. Results The average annual positive rate of measles antibody was 85.5% and the geometric mean concentration (GMC) was 819mIU / ml. The average prevalence rate of measles antibody was 84.0% and the GMC was 823 mIU / ml in younger age group. The average positive rate of measles antibody in adults over the age of 15 was 87.9% and the GMC was 811 mIU / ml. Among them, the antibody level of people under 2 years of age and 15 ~ 34 years old is relatively low. The positive rates of measles antibody and GMC in different age groups, different regions, floating population and resident population were all significantly different; there was no significant difference between different genders and ethnic groups. Conclusion: People under 2 years of age and 15 to 34 years old are the high incidence of measles. In some remote areas of South Xinjiang and the floating population, the basic immunization is weak. Corps control of measles should focus on such key populations.