胰腺癌恶性程度高,病死率约占年发病率的98%,早期即可发生转移,加上缺乏有效的早期诊断手段,手术切除率极低,只有10%～15%左右的病人在明确诊断时得到根治性切除,且术后5年存活率也仅为5%～20%[1]。目前临床研究表明胰腺癌淋巴结转移是影响手术治疗和预后的重要因素,也是国内外胰腺癌研究的热点。近年来,随着手术治疗的进展和分子生物学及病理学技术的飞速发展,这一研究领域又取得了新的进展。综述如下。 Pancreatic cancer has a high degree of malignancy and a mortality rate of about 98% of the annual incidence, early metastasis, coupled with the lack of effective early diagnosis, surgical resection rate is very low, only 10% to 15% of patients in a clear diagnosis When the radical resection, and 5-year survival rate of only 5% to 20% [1]. At present, clinical studies have shown that lymph node metastasis of pancreatic cancer is an important factor affecting the surgical treatment and prognosis, but also the hot spots of pancreatic cancer research at home and abroad. In recent years, with the progress of surgical treatment and the rapid development of molecular biology and pathology, new progress has been made in this field. Summarized as follows.