消化道肿瘤是严重威胁人类的主要肿瘤 ,特别是晚期恶性消化道肿瘤 ,临床确诊时手术时机往往丧失 ,放疗、化疗又不甚敏感 ,为提高治疗的有效率和患者的生存期 ,人们一直在探索新的治疗策略。在现代分子生物学和基因工程技术飞速发展的推动下 ,以免疫治疗为基础发展而来的生物治 Gastrointestinal cancer is a serious threat to humans, the main tumor, especially advanced malignant gastrointestinal tumors, clinical diagnosis of the timing of surgery is often lost, radiotherapy, chemotherapy and less sensitive, in order to improve the efficiency of treatment and patient survival, people have been Explore new treatment strategies. In the modern rapid development of molecular biology and genetic engineering technology, driven by the development of immunotherapy based on biological treatment