作者曾报道,糖耐量异常的非肥胖者其血浆胰岛素水平、甘油三酯浓度以及血压均比糖耐量正常的对照者明显升高。作者推测糖耐量异常的人,其基本缺陷是胰岛素促进的葡萄糖摄取障碍和高胰岛素血症;脂质代谢和血压的变化系由高胰岛素血症所致。如果这一假设正确,那么糖耐量正常的高胰岛素血症者亦应有脂质代谢和血压调控的异常。 作者从247名精耐量正常的健康人中选译32名 The authors have reported that non-obese patients with impaired glucose tolerance had significantly elevated plasma insulin levels, triglyceride concentrations, and blood pressure compared with those with normal glucose tolerance. The authors speculate that people with impaired glucose tolerance have an underlying defect in impaired glucose uptake by insulin and hyperinsulinemia; changes in lipid metabolism and blood pressure result from hyperinsulinemia. If this assumption is correct, hyperinsulinism with normal glucose tolerance should also have lipid metabolism and abnormalities in blood pressure regulation. The authors selected 32 out of 247 healthy and well-to-do people