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随着全球消灭脊髓灰质炎(脊灰)活动进入到最后阶段,世界各地陆续发现了多例免疫缺陷病患者排出的疫苗衍生脊灰病毒(Vaccine-derived Poliovirus,VDPV)。由于此类病例能够长期携带并向环境中排出VDPV,各国开始关注免疫缺陷病患者排出PV的问题,并对消灭脊灰后的免疫策略重新进行思考。
With the global eradication of poliomyelitis (polio) entering the final stage, several vaccine-derived poliovirus (VDPV) released from patients with immunodeficiency have been discovered around the world. Since such cases can carry VDPV long-term and to the environment, countries are beginning to pay attention to the issue of PV in patients with immunodeficiency disease and to rethink the immunization strategies after polio eradication.