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目的:观察C-反应蛋白与体重指数、腰围、臀围及糖、脂代谢等指标间的相关性,探讨C-反应蛋白与2型糖尿病的关系。方法:将131例受检对象分为肥胖2型糖尿病组、非肥胖2型糖尿病组、单纯肥胖组及对照组,测定体重指数、腰围、臀围、及糖代谢、脂代谢指标、C-反应蛋白等,以HOMA-IR及ISI来评价胰岛素的敏感性。结果:12型糖尿病组CRP及胰岛素抵抗指数均高于对照组(P<0.05);肥胖者的CRP及胰岛素抵抗指数均高于非肥胖者(P<0.05);2BMI、ISI为血CRP水平的影响因素;3Logistic多元回归显示:HOMA-IR(OR=106.696)、CRP(OR=6.239)、TG(OR=6.923)是2型糖尿病的危险因素。
Objective: To observe the correlation between C-reactive protein and body mass index, waist circumference, hip circumference, glucose and lipid metabolism, and to explore the relationship between C-reactive protein and type 2 diabetes mellitus. Methods: 131 subjects were divided into obese type 2 diabetic group, non-obese type 2 diabetic group, simple obesity group and control group. Body mass index, waist circumference, hip circumference, glucose metabolism, lipid metabolism index, C- Protein, etc., HOMA-IR and ISI to evaluate the sensitivity of insulin. Results: CRP and insulin resistance index of type 2 diabetes mellitus group were higher than that of control group (P <0.05); CRP and insulin resistance index of obese group were higher than that of non-obese group (P <0.05); 2BMI and ISI were CRP 3 Logistic multiple regression analysis showed that HOMA-IR (OR = 106.696), CRP (OR = 6.239) and TG (OR = 6.923) were the risk factors for type 2 diabetes.