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目的探讨脑梗死与颈动脉粥样硬化斑块的相关性。方法 200例脑梗死患者(脑梗死组),采用彩色多普勒血流成像技术观察其颈动脉内中膜厚度、斑块部位、大小及其数目、动脉狭窄程度及血流动力学改变等指标;200例同期住院非脑血管疾病患者为对照组,比较2组颈动脉粥样硬化斑块发生率及斑块性质差异。结果脑梗死组颈动脉粥样硬化斑块发生率(71.00%)高于对照组(21.50%)(P<0.05),软斑块发生率(42.96%)明显高于对照组(23.26%)(P<0.05);脑梗死组中以软斑和混合斑发生率较高,对照组则以扁平斑和硬斑多见。结论脑梗死发生与颈动脉粥样硬化斑块形成相关,且软斑较扁平斑块更易发生脑梗死。
Objective To investigate the correlation between cerebral infarction and carotid atherosclerosis plaque. Methods 200 patients with cerebral infarction (cerebral infarction group) were examined by color Doppler flow imaging to observe the carotid intima-media thickness, plaque site, size and number, arterial stenosis and hemodynamic changes ; 200 cases of hospitalized patients with non-cerebrovascular disease in the same period as the control group, compared two groups of carotid atherosclerosis plaque incidence and plaque quality differences. Results The incidence of carotid atherosclerotic plaques in cerebral infarction group was significantly higher than that in control group (71.00% vs. 21.50%, P <0.05), and the incidence of soft plaque (42.96%) was significantly higher than that in control group (23.26%) P <0.05). In the cerebral infarction group, the incidence of soft plaque and mixed plaque was higher than that in the control group. Conclusions The occurrence of cerebral infarction is related to the formation of carotid atherosclerosis plaque, and the soft plaque is more prone to cerebral infarction than the flat plaque.