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目的探讨D-二聚体检测在难治性支原体肺炎中的意义。方法选取许昌市中心医院2013年8月—2015年8月收治的难治性支原体肺炎患儿48例,分别在入院时及恢复期时抽取外周静脉血测定血浆D-二聚体水平,同时随机选取50例同期正常儿童体检血液标本作为对比。结果研究组入院时和恢复时D-二聚体浓度有统计学差异(t=5.016,P<0.05);研究组入院时与对照组D-二聚体浓度比较也有统计学差异(t=5.203,P<0.05);研究组恢复时与对照组D-二聚体浓度比较无统计学差异(t=0.019,P>0.05)。结论通过D-二聚体水平的检测,能够直观的反应患儿体内的炎症反应和凝血状态,可为难治性支原体肺炎的临床治疗提供判断和监测的依据。
Objective To investigate the significance of D-dimer in refractory mycoplasma pneumonia. Methods 48 patients with refractory mycoplasma pneumonia admitted in Central Hospital of Xuchang from August 2013 to August 2015 were enrolled in this study. Peripheral venous blood was collected for the determination of plasma D-dimer at admission and during convalescence, Select 50 cases of normal children during the same period as the contrast blood test. Results There was a significant difference in the concentration of D-dimer between the study group and the control group (t = 5.016, P <0.05). There was also a significant difference in the concentration of D-dimer between the study group and the control group (t = 5.203 , P <0.05). There was no significant difference in D-dimer concentration between the study group and the control group (t = 0.019, P> 0.05). Conclusion The detection of D-dimer level can intuitively reflect the inflammatory reaction and coagulation state in children and provide the basis for judging and monitoring the clinical treatment of refractory mycoplasma pneumonia.