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目的研究血中高敏C反应蛋白(high sensitive C-reactive protein,hs-CRP)与老年高血压患者肾脏功能之间的关系。方法对符合入选条件的210例老年高血压患者进行hs-CRP水平测定,根据肌酐水平估测肾小球滤过率(estimated glomerular fi ltration rate,eGFR),比较不同肾功能状态患者hs-CRP水平并进行相关分析。结果肾功能减退患者hs-CRP水平增加,尤其是eGFR<60ml/(min·1.73m2)患者hs-CRP水平明显增高(P<0.05)。结论在老年高血压患者中hs-CRP水平变化能够反映高血压患者肾脏功能状态的变化,可作为高血压健康管理的动态随访指标。
Objective To study the relationship between high sensitive C-reactive protein (hs-CRP) and renal function in elderly hypertensive patients. Methods The hs-CRP levels were measured in 210 elderly hypertensive patients who met the inclusion criteria. The estimated glomerular fi ltration rate (eGFR) was estimated according to the creatinine level. The hs-CRP levels in patients with different renal function were compared And make relevant analysis. Results The level of hs-CRP in patients with renal dysfunction increased, especially in patients with eGFR <60ml / (min · 1.73m2), the hs-CRP level was significantly increased (P <0.05). Conclusion The changes of hs-CRP level in elderly patients with hypertension can reflect the changes of renal functional status in patients with hypertension, and can be used as a dynamic follow-up index of hypertension health management.