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在卵巢肿瘤发生、发展过程中HER2/neu基因呈高水平表达状态〔1,2〕,通过其反义寡聚核苷酸处理卵巢肿瘤细胞株3ao10/3以探讨靶基因表达水平降低对卵巢肿瘤细胞增殖的影响。1材料与方法1-1材料卵巢肿瘤细胞株3ao10/3购自中科院细胞所,反义HE
HER2 / neu gene is highly expressed in the development and progression of ovarian tumors [1, 2], ovarian cancer cell line 3ao10 / 3 is treated by its antisense oligonucleotide to investigate the reduction of target gene expression Ovarian tumor cell proliferation. 1 Materials and Methods 1-1 Materials ovarian cancer cell line 3ao10 / 3 purchased from the Chinese Academy of Sciences, the antisense HE