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1985年我院应用炔羟雄烯异恶唑(丹那唑——人工合成的,减弱了男性化作用的雄性激素)治疗13例特发性血小板减少性紫癜(ITP),现报告如下:临床资料 13例中男5例,女8例;年龄为9~57岁,中位数年龄43岁,除1例9岁、1例12岁外,余均为成年患者。ITP 诊断依据为:(1)血小板数少于100×10~9/L;(2)骨髓巨核细胞增多和成熟障碍;(3)无大脾和白细胞数减低。治疗前血小板数为12~69
In 1985, our hospital treatment of 13 cases of idiopathic thrombocytopenic purpura (ITP) with alkyne androstane isoxazole (Danazol - a synthetic and reduced masculinization of male hormones) are as follows: Clinical data 13 cases of 5 males and 8 females; aged 9 to 57 years, the median age of 43 years, except for 1 case of 9 years old, 1 case of 12 years of age, the remaining were adult patients. ITP diagnosis based on: (1) platelet count less than 100 × 10 ~ 9 / L; (2) increased bone marrow megakaryocytes and maturation; (3) no spleen and white blood cells decreased. The number of platelets before treatment was 12-69