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目的 :探讨与原发性肺癌发生有关的因素 ,为预防肺癌提供科学依据。方法 :采用 1∶ 2配对病例 -对照研究方法进行研究 ,应用多因素条件 L ogistic回归模型分析与肺癌发生有关的因素 ,并对肺癌危险因素的人群归因危险度 ( PAR)进行估计。结果 :筛选出 8个与肺癌有关的因素 ,其中吸烟、离退休、工作场所有毒物质、肺结核病史、常做饭菜、使用煤炭等因素增加肺癌的危险性 ,其危险度 ( OR)分别是 :2 .3 78,2 .3 18,2 .2 62 ,1.975 ,1.793 ,1.75 6,人群归因危险度分别是 :3 8.0 9% ,2 3 .3 0 % ,19.2 0 % ,13 .76% ,2 3 .2 1% ,15 .5 3 % ,6项危险因素总的人群归因危险度为 76.95 % ;而居室通风良好、常食用水果能降低肺癌的危险性 ,其危险度 ( OR)分别是 :0 .5 17,0 .70 2。结论 :吸烟、离退休、工作场所存在有毒物质、有肺结核病史、常做饭菜、使用煤炭等是肺癌的危险因素 ,如果消除这些因素可使人群中肺癌的发生减少 76.95 % ;而居室通风良好、常食用水果是肺癌的保护因素
Objective: To explore the factors related to the occurrence of primary lung cancer and provide scientific basis for the prevention of lung cancer. METHODS: A 1:2 matched case-control study was performed. Multivariate conditional logistic regression models were used to analyze factors associated with lung cancer development and population risk factors for lung cancer (PAR) were estimated. RESULTS: Eight factors related to lung cancer were screened out, including smoking, retirement, all toxic substances in the workplace, history of tuberculosis, frequent meals, and the use of coal, which increased the risk of lung cancer. The risk (OR) was: 2 .3 78,2 .3 18,2 .2 62 ,1.975 ,1.793 ,1.75 6. Crowd attributive risk was: 3 8.0 9%, 2 3. 3 0 %, 19.20 %, 13.76%. 23.2% 1%, 15.53%, 6 risk factors total population attributable risk of 76.5%; and good ventilation and regular consumption of fruits can reduce the risk of lung cancer, the risk (OR) It is: 0 .5 17,0 .70 2. Conclusion: Smoking, retiring, toxic substances in the workplace, history of tuberculosis, frequent cooking, and use of coal are risk factors for lung cancer. If these factors are eliminated, the occurrence of lung cancer in the population will be reduced by 76.9%; and the ventilation of the living room will be good. Regular consumption of fruits is a protective factor for lung cancer