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聚合物胶束(polymeric micelles,PMs)作为一种新型的纳米载体具有很多的优势,能够通过被动靶向、主动靶向及物理化学敏感等方式递送药物至靶位并控制释药,可装载多种物质如抗肿瘤药物、显影剂、基因药物等,应用广泛尤其是用于肿瘤的诊断和治疗。本文首先对PMs的基本知识进行了简单介绍,并重点综述了PMs作为一种新型纳米载体在肿瘤治疗与诊断方面的应用,为肿瘤的治疗提供新的思路和依据。
Polymeric micelles (PMs) have many advantages as a new type of nanocarriers. They can deliver drugs to target sites and control drug release by passive targeting, active targeting and physicochemical sensitization, and can load more Species such as anti-cancer drugs, developers, gene drugs, etc., is widely used, especially for the diagnosis and treatment of tumors. In this paper, the basic knowledge of PMs is briefly introduced, and the application of PMs as a new type of nanocarriers in the treatment and diagnosis of tumors is emphatically reviewed, providing new ideas and bases for the treatment of tumors.