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为了解婴儿肺炎中沙眼衣原体(CT)感染情况,探讨患儿血清中特异性IgM对CT肺炎的诊断价值,应用ELISA法检测肺炎患儿血清中CT特异性IgM,同时对患儿鼻咽部分泌物(NPS)进行CT分离,特异性单克隆荧光抗体(MFA)鉴定。结果:49例患儿中9例(18.4％)于病程早期(5天～7天)存在高效价IgM,此9名患儿NPS中细胞学分离CT阳性。结论:CT特异性IgM于病程早期升高,可以证明患儿存在CT近期感染,若细胞学分离阳性即能明确诊断。
To understand the infection of C. trachomatis (CT) in infantile pneumonia, to explore the diagnostic value of serum specific IgM in CT pneumonia, to detect the serum CT-specific IgM in children with pneumonia by ELISA and to detect the nasopharyngeal secretions (NPS) CT separation, specific monoclonal antibody (MFA) identification. RESULTS: Nine of 49 children (18.4%) had high titer of IgM at early stage of disease (5 days to 7 days). The cytology was positive for CT in 9 of 9 children. Conclusion: CT-specific IgM increased early in the course of the disease, which can prove the presence of CT in children with recent infection, if the cytology can be a positive diagnosis that a clear diagnosis.