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目的探讨依伦平治疗高血压及逆转左室肥厚的效果。方法将90例伴有左心室肥厚的高血压患者随即分成2组,依伦平组45例,用依伦平150mg,(江苏正大天晴药业)苯磺酸氨氯地平组45例,用苯磺酸氨氯地平5mg,(辉瑞制药有限公司)均1次/d,晨服,疗程24周。观察用药前后血压、左心室重量指数(LVMI)等指标变化。结果 2组患者治疗后血压、室间隔及左室后壁厚度、左室重量指数等指标均较用药前显著下降。结论依伦平可减轻高血压患者左心室肥厚,且能显著降低血压,不良反应相对较小。
Objective To investigate the effect of Elanping on hypertension and reversing left ventricular hypertrophy. Methods Ninety hypertensive patients with left ventricular hypertrophy were randomly divided into two groups: 45 patients in the elanping group, 45 patients in the amilipine besylate group (n = 150), 45 patients in the amlodipine besylate group Amlodipine besylate 5mg, (Pfizer Pharmaceutical Co., Ltd.) were 1 / d, morning service, treatment for 24 weeks. Before and after treatment of blood pressure, left ventricular mass index (LVMI) and other indicators change. Results After treatment, blood pressure, interventricular septum, left ventricular posterior wall thickness, left ventricular mass index and other indicators were significantly decreased in both groups after treatment. Conclusion Elanping can reduce left ventricular hypertrophy in patients with hypertension, and can significantly lower blood pressure, adverse reactions are relatively small.