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目的:探讨本地区变应性鼻炎(AR)并发支气管哮喘(BA)的发病率,以及AR并发BA患者在年龄、不同分型、并发症3方面的疾病相关性。方法:通过随机抽取、体格检查、必要的实验室手段、填写调查问卷几种方法,确诊本地区489例AR,并依据BA的诊断标准,将其分为2组,Ⅰ组(对照组)为仅有AR的患者298例,Ⅱ组(试验组)指AR并发BA者191例,进行2组对比分析。结果:①本组资料表明;AR并发BA者占39%;②哮喘-鼻息肉-阿司匹林过敏(ASA)三联症,2组差异有统计学意义(P<0.01);③年龄组人数分布,10～19岁及40～49岁2组差异有统计学意义(P<0.05);④疾病分型,中重度间歇性AR、轻度持续性AR、中重度持续性AR三型实验组和对照组间差异有统计学意义(P<0.05);⑤其他主要伴发病及症状2组分布情况,如变应性咽炎、鼻窦炎、结膜炎、分泌性中耳炎、肥厚性鼻炎、皮肤病、胃肠道不适症状、不明原因头痛2组差异有统计学意义(P<0.05),以上差异性都表明实验组高于对照组。结论:本地区AR并发BA者人数较高,并发BA者以10～19岁及40～49岁者较多,分型以中重度间歇性AR、轻度持续性AR、中重度持续性AR3型比较多见,并发BA者伴发疾病人数增加。
OBJECTIVE: To investigate the incidence of allergic rhinitis (AR) complicated with bronchial asthma (BA) in the region and the relationship between age, disease type, and complications in patients with AR complicated with BA. Methods: A total of 489 AR patients in our area were diagnosed by random sampling, physical examination, necessary laboratory methods and several questionnaires. According to the diagnostic criteria of BA, the patients were divided into two groups. Group Ⅰ (control group) was Only 298 patients with AR, Ⅱ group (test group) with AR complicated with BA in 191 cases, the two groups were analyzed. Results: ① The data of this group showed that 39% of patients with AR complicated with BA had asthma-nasal polyps-ASA triad, the difference between the two groups was statistically significant (P <0.01); ③The number distribution of age group, 10 There were significant differences between the two groups (~ 19 years old and 40-49 years old) (P <0.05); ④The classification of disease, moderate and severe intermittent AR, mild persistent AR, moderate and severe persistent AR type III experimental group and control group (P <0.05); ⑤the distribution of other major companion diseases and symptoms, such as allergic pharyngitis, sinusitis, conjunctivitis, secretory otitis media, hypertrophic rhinitis, skin diseases, gastrointestinal tract Symptoms of unwell, unexplained headache in two groups were statistically significant differences (P <0.05), the above differences show that the experimental group was higher than the control group. CONCLUSIONS: The number of AR complicated with BA in this area is relatively high, and those with complicated BA are mostly aged 10 to 19 years and 40 to 49 years old. The patients with moderate to severe intermittent AR, mild persistent AR, moderate to moderate persistent AR3 More common, complicated with increased number of patients with BA.