膈肌功能是机械通气患者能够成功脱机的重要决定因素。在临床上,机械通气患者膈肌功能障碍可能是脱机失败的一个重要原因。Vassilakopoulos等[1]称之为呼吸机相关膈肌功能障碍(ventilator-induced diaphragmatic dysfunctionVIDD)。来自动物模型的大量证据,以及人类的有限数据表明,机械通气可导致膈肌纤维损伤和膈肌内在萎缩。虽然我 Diaphragm function is an important determinant of the success of mechanically ventilated patients. Clinically, diaphragmatic dysfunction in mechanically ventilated patients may be an important cause of offline failure. Vassilakopoulos et al [1] called ventilator-induced diaphragmatic dysfunctionVIDD. Numerous evidence from animal models and limited human data suggest that mechanical ventilation can lead to diaphragmatic muscle damage and diaphragmatic atrophy. Although I