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目的观察布地奈德吸入对围术期支气管哮喘患者急性发作的干预作用。方法将126例围术期支气管哮喘患者随机分为二组,观察组吸入布地奈德,对照组吸入生理盐水,每日记录二组症状体征变化及最大呼气流速(PEF)值,计算术后二组支气管哮喘急性发作率并进行比较,同时比较二组术前术后PEF值。结果术前对照组PEF为(429±85)L/min,观察组为(402±74)L/min,二组相比差异无统计学意义(P>0.05),术后对照组支气管哮喘急性发作率为43.3%,观察组为7.5%,二组对比差异有统计学意义(P<0.05),术后对照组PEF为(290±45)L/min,观察组为(365±66)L/min,二组对比差异有统计学意义(P<0.05)。结论支气管哮喘患者围术期吸入布地奈德能有效的降低支气管哮喘急性发作率。
Objective To observe the effect of inhalation of budesonide on the acute attack of perioperative bronchial asthma. Methods A total of 126 patients with perioperative bronchial asthma were randomly divided into two groups. The patients in the observation group inhaled budesonide. The control group received physiological saline. The symptoms and signs and the maximum expiratory flow rate (PEF) The acute exacerbation rate of bronchial asthma in the two groups were compared and compared. The PEF values of the two groups before and after operation were also compared. Results The preoperative control group had a PEF of (429 ± 85) L / min and the observation group (402 ± 74) L / min, with no significant difference between the two groups (P> 0.05). The postoperative acute bronchial asthma (P <0.05). The postoperative PEF was (290 ± 45) L / min in the control group and (365 ± 66) L in the observation group, with an incidence of 43.3% in the observation group and 7.5% in the observation group / min, the difference between the two groups was statistically significant (P <0.05). Conclusions Perioperative inhalation of budesonide can effectively reduce the acute attack rate of bronchial asthma in patients with bronchial asthma.