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目的:了解我院呼吸科和重症监护病房(ICU)科室住院患者抗菌药应用情况,分析其用药合理性。方法:抽查2010年5～6月呼吸科和ICU住院患者病历,对患者的特征和抗菌药使用情况进行统计分析。结果:呼吸科实施抗感染治疗180例,抗菌药使用率96.8%,青霉素类/酶抑制药使用率最高,单一用药38例(21.1%),二联用药100例(55.6%),三联及以上用药42例(23.3%),病原学检测送检率86.7%,平均用药疗程11.4 d;ICU实施抗感染治疗18例,抗菌药使用率81.8%,头孢菌素类使用率最高,单一、二联、三联用药各6例(各占33.3%),病原学检测送检率100%,平均用药疗程44.3d。结论:我院呼吸科和重症监护病房(ICU)存在抗菌药使用率偏高,部分病例无指征联合用药、更换药物频繁且无指征或依据,“特殊使用”类抗菌药缺乏专家会诊记录等问题,应进一步加强抗菌药合理应用管理。
Objective: To understand the application of antibacterials in hospital patients in respiratory department and intensive care unit (ICU) in our hospital and analyze its rationality. Methods: The medical records of inpatients in respiratory department and ICU from May to June in 2010 were randomly selected. The characteristics of patients and the use of antibacterials were analyzed statistically. Results: 180 cases of anti-infectives were treated in respiratory department, the use rate of antibacterials was 96.8%, and that of penicillins / enzyme inhibitors was the highest, 38 cases (21.1%) were treated with single drug, 100 cases (55.6% 42 cases (23.3%) were treated with etiology, 86.7% were etiologically tested and the average course of treatment was 11.4 days. Anti-infective treatment in ICU was performed in 18 cases, antibacterial drug use rate was 81.8%, cephalosporin use rate was the highest, , Triple drug use in 6 cases (33.3% each), etiological test delivery rate of 100%, the average medication course of 44.3d. CONCLUSIONS: The use of antibacterials in respiratory department and intensive care unit (ICU) in our hospital is high. In some cases, there is no indication for combination therapy. Frequent replacement of drugs and no indications or evidences, and lack of special-use antimicrobial agents Consultation records and other issues, we should further strengthen the rational application of antibacterial management.