连续血液净化治疗重症急性胰腺炎的临床疗效

来源 :中国药物经济学 | 被引量 : 0次 | 上传用户:bird2000521
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目的探讨连续血液净化治疗重症急性胰腺炎的临床疗效。方法选取2012年1月至2013年12月我院收治的重症急性胰腺炎患者34例,随机将其分为两组。对照组患者给予规范化综合治疗,观察组患者在对照组基础上给予连续血液净化治疗,比较两组患者的临床症状恢复时间及治疗前、治疗3 d后血清淀粉酶、血清降钙素原(PCT)、氧合指数水平。结果观察组患者呕吐、腹痛、腹胀、发热症状恢复时间均短于对照组;观察组患者血清淀粉酶、PCT水平明显低于对照组;观察组患者氧合指数明显高于对照组,差异均有统计学意义(均P<0.05)。结论连续血液净化治疗重症急性胰腺炎可改善患者的临床症状,清除体内的血清淀粉酶、PCT,改善氧合指数。 Objective To investigate the clinical efficacy of continuous blood purification in the treatment of severe acute pancreatitis. Methods From January 2012 to December 2013, 34 patients with severe acute pancreatitis admitted to our hospital were randomly divided into two groups. Patients in the control group were treated with continuous blood purification on the basis of the control group. The recovery time of clinical symptoms and the serum amylase, ), Oxygenation index level. Results The recovery time of vomiting, abdominal pain, abdominal distension and fever were all shorter in the observation group than in the control group. The serum amylase and PCT levels in the observation group were significantly lower than those in the control group. The oxygenation index in the observation group was significantly higher than that in the control group Statistical significance (all P <0.05). Conclusion Continuous blood purification of severe acute pancreatitis can improve the clinical symptoms of patients, clear the body of serum amylase, PCT, improve oxygenation index.
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