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1976年4～6月美国新泽西州进行了一次流感疫苗现场试验,以评价A/NJ/76流感疫苗(简称猪流感疫苗)对成人及儿童的保护力,共观察了成人3982例和儿童1204例,并对其与A/Victoria/75流感疫苗(简称甲型流感疫苗)和B/香港/73流感疫苗(简称乙型流感疫苗)的联合免疫效力进行了研究。成人以三种剂量接种A/NJ/76流感疫苗:200、400和800CCA(鸡胚细胞凝集单位)/0.5毫升。用缓冲盐水作安慰剂对照。接种后以血凝抑制试验测定血清抗体。结果表明,抗体阳性率随年龄增长而升高:17～
From April to June 1976, a field trial of influenza vaccine was conducted in New Jersey, USA to evaluate the protective effect of A / NJ / 76 influenza vaccine on adults and children. A total of 3982 adults and 1204 children And studied its combined immunization efficacy against A / Victoria / 75 influenza vaccine (Influenza A) and B / Hong Kong / 73 influenza vaccine (Influenza B vaccine). Adults received the A / NJ / 76 influenza vaccine at three doses: 200, 400 and 800 ccA (chicken blast agglutination units) / 0.5 ml. Placebo control with buffered saline. After inoculation hemagglutination inhibition test to determine serum antibody. The results showed that the positive rate of antibody increased with age: 17 ~