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目的：总结颅骨缺损合并脑积水的同期行分流与颅骨修补术治疗的临床经验。方法回顾性分析39例同期行脑室腹腔分流及颅骨修补手术的颅脑损伤病例，对其临床资料、并发症及其预后进行总结。结果术后无颅内感染，术后82．1％患者意识及神经功能障碍不同程度改善。结论颅脑损伤术后颅骨缺损、脑积水、脑膨出严重影响患者预后，同期行脑室腹腔分流及颅骨修补手术并发症少，可明显改善患者意识及神经功能障碍，改善患者预后，值得推广。“,”Objective To summarize clinical experiences of synchronization cranioplasty and ventricul operitoneal shunt for treatment of patient with skull defect complicated hydrocephalus .Methods Retrospect study was made on 39 patients who were found to have hydrocephalus after the surgical intervention of the traumatic brain injury complicated by skull defect .Results The intracranial infection did not occurred in all cases .82.1%patients had improvement with consciousness and nerve dysfunction after operation .Con-clusion The complications of skull defect ,brain swelling and hydrocephalus after traumatic brain injury operation will seriously threat the patient′s prognosis .One-stage ventriculo-peritoneal shunt and cranioplasty , causing few complications , can improve patients′con-sciousness,nerve function and outcome,and hence,is worthy of recommendation.