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目的探讨显微外科技术经鼻蝶治疗垂体瘤的临床疗效。方法对我院神经外科2013年2月至2014年2月行显微手术治疗50例垂体瘤患者的临床资料进行回顾性分析,探讨临床治疗效果,并分析手术对各个症状不同改善率。结果手术中无1例患者死亡,全部患者均顺利完成手术,手术时间为30~45 min,平均(40±4)min;住院时间为6~9 d,平均(7.5±0.3)d;治疗总有效率为82.0%。所有患者术后无脑脊液漏、颅内感染以及蛛网膜下腔出血等严重并发症发生。结论显微外科经鼻蝶治疗垂体瘤临床效果理想,能够明显改善患者的症状,且操作简便,创伤小,术后无严重并发症。通过详细了解手术适应证,提高术中操作的规范性,显微外科治疗可作为临床垂体瘤治疗理想方式。
Objective To investigate the clinical effect of microsurgical treatment of pituitary tumor by nasal butterfly. Methods The clinical data of 50 patients with pituitary adenoma treated by microsurgery in our department from February 2013 to February 2014 were retrospectively analyzed to discuss the clinical effect and the rate of improvement of each symptom. Results None of the patients died during the operation. All the patients were successfully performed the operation. The operation time was 30-45 min (mean, 40 ± 4) min. The length of stay was 6-9 days (mean, 7.5 ± 0.3) days. The total treatment The effective rate is 82.0%. All patients without cerebrospinal fluid leakage, intracranial infection and subarachnoid hemorrhage and other serious complications. Conclusion Microsurgical treatment of pituitary tumors with nasal papillae is clinically effective and can significantly improve the symptoms of the patients. The operation is simple, less traumatic and no serious postoperative complications. Through detailed understanding of surgical indications and improve the normative operation of surgery, microsurgery can be used as an ideal way of clinical treatment of pituitary tumors.