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前列环素(Prostacyclin PGI_2)和血栓素A_2(Phromboxane TxA_2)是迄今已知的,具有调控血小板功能最强的一对内源性前列腺素物质。环孢素(Cyclosporine CsA)是一种较新的免疫抑制剂。自从 Calne 等首先将 CsA 应用于肾移植临床以后,受到了移植工作者的普遍重视。CsA 使移植体的1~2年存活率较
Prostacyclin PGI_2 and Phromboxane TxA_2 are a pair of endogenous prostaglandins known to date that have the strongest regulatory function of platelets. Cyclosporine CsA is a newer immunosuppressant. Since the first application of CsA by Calne et al in renal transplantation, it has received widespread attention from transplant workers. CsA graft survival rate of 1 to 2 years