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研究体外冲击波冲击对新西兰兔肝胆组织细胞超微结构的影响。冲击波冲击时间为０、１５、３０和４５ ｍｉｎ，冲击波能量储存读数分别为０、７．８、１５．６和２３．５。作用后立即处死动物，在透射电镜下观察。结果：胆囊上皮细胞不同程度变性，表现为内质网、线粒体肿胀及基质变淡；细胞侧面的连接结构消失，间隙增宽；有的细胞分离、脱落。肝细胞能观察到肿胀、核固缩和质膜破裂等改变．能量越强，改变越严重。冲击波作用后２、４、６和１４个月，上述改变和损伤大部分可逆变，在电镜下观察到损伤修复恢复正常的过渡细胞，在１４个月时，所有细胞恢复正常。结论：实验支持体外冲击波碎石术在临床应用，但应尽量避免对肝胆组织的过度冲击，以免产生严重的细胞损伤。
To study the effect of shock wave in vitro on the ultrastructure of hepatobiliary cells in New Zealand rabbits. Shock wave impact time is 0, 15, 30 and 45 min, and shock wave energy storage readings are 0, 7.8, 15.6 and 23.5, respectively. Immediately after the animals were sacrificed, they were observed under a transmission electron microscope. Results: Gallbladder epithelial cells degenerated to varying degrees, showing the endoplasmic reticulum, mitochondrial swelling and matrix fades; the side of the cell structure disappeared, the gap widened; and some cells isolated and shedding. Liver cells can be observed swelling, nuclear condensation and plasma membrane rupture and other changes. The stronger the energy, the more severe the change. At 2, 4, 6 and 14 months after shock wave, most of the above changes and lesions were reversible. All the cells returned to normal after 14 months of injury. Conclusion: Experimental support for extracorporeal shock wave lithotripsy in clinical application, but should try to avoid excessive impact on hepatobiliary tissue, so as to avoid serious cell damage.