论文部分内容阅读
肝纤维化是各种慢性肝病向肝硬变发展的必经阶段。探讨早期诊断肝纤维化,动态观察肝纤维化过程的临床指标,是近年来颇受重视的研究课题之一。国内外许多学者报道,血清Ⅲ型前胶原肽(PⅢP)是诊断肝纤维化较好的血清学指标,但因PⅢP进口药盒价格昂贵,不易推广应用。我们应用国产血清Ⅲ型前胶原(PCⅢ)试剂盒测定了116例慢性肝炎、肝硬化患者的PCⅢ含量,以探讨PCⅢ测定在肝纤维化诊断中的意义。
Liver fibrosis is a necessary stage for the development of various chronic liver diseases toward cirrhosis. To explore the early diagnosis of liver fibrosis, dynamic observation of the clinical indicators of liver fibrosis process, is one of the most important research topics in recent years. Many scholars at home and abroad reported that serum type Ⅲ procollagen peptide (P Ⅲ P) is a good serological indicator for diagnosing liver fibrosis. However, it is not easy to popularize because P Ⅲ P import kit is expensive. We use the national serum type Ⅲ procollagen (PC Ⅲ) kit determination of 116 cases of chronic hepatitis, cirrhosis of patients with PC Ⅲ content in order to explore the significance of PC Ⅲ in the diagnosis of liver fibrosis.