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Barrett食管(BE)是指食管下段的正常鳞状上皮被覆柱状上皮取代的一种病理状态[1]。常被认为是一种癌前期的组织学改变,其发生食管癌的危险性较一般人群高30~50倍。现行的治疗方法主要是抑酸药物治疗和外科食管切除术,但前者仅可缓解症状,而无法逆转其肠上皮化生转为Barrett食管
Barrett’s esophagus (BE) is a pathologic condition where the normal squamous epithelium-covered columnar epithelium is replaced by the lower esophagus [1]. Often considered a precancerous histological change, the risk of esophageal cancer 30 to 50 times higher than the general population. The current treatment is mainly acid suppression drug therapy and surgical esophagectomy, but the former can only relieve the symptoms, but can not reverse the intestinal metaplasia to Barrett esophagus