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目的 评价NVB与DDP联合治疗NSCLC的疗效及毒副反应。方法 将 89例NSCLC患者随机分为A、B两组 ,A组 46例用NP方案 ,B组 43例用EP方案 ,将两组疗效及毒副反应进行比较。结果 A组总有效率为 41.3% ,B组为 2 0 .9%。白细胞减少是限制药物剂量主要毒性 ,B组较A组显著。结论 NP方案治疗NSCLC疗效优于EP方案。
Objective To evaluate the curative effect and toxicity of combined treatment of NVB and DDP on NSCLC. Methods 89 patients with NSCLC were randomly divided into A and B groups, 46 patients in group A received NP regimen and 43 patients in group B received EP regimen. The curative effect and toxicity were compared between the two groups. Results The total effective rate in group A was 41.3% and that in group B was 20.9%. Leukopenia is the main dose-limiting drug toxicity, B group significantly more than the A group. Conclusion NP regimen is superior to EP regimen in treating NSCLC.