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伦敦大学学院Bonati LH博士等10月14日在线发表于Lancet的ICSS试验结果显示,症状性颈动脉狭窄(SCAS)患者中,在长期功能预后和致死性出血或致残性卒中风险方面,支架置入术的效果与动脉内膜切除术相当。研究者从50个国际中心随机入选1713例SCAS患者,以1:1比例分至支架置入组(n=855)或动脉内膜切除术组(n=858)。研究者对最终完成31天治疗的1710例患者行完成治疗分析和意向治疗分析(ITT)。随机化后发生的致死性或致残性卒中为主要终点。随访4.2年。研究显示,支架植入组和动脉内膜切除术组发生致死
Results from the ICSS trial published online in Lancet, October 14, by Bonati LH, Ph.D., University College London, showed that in patients with symptomatic carotid stenosis (SCAS), in terms of long-term functional outcome and the risk of fatal bleeding or disabling stroke, stent placement The effect of surgery is similar to that of endarterectomy. The researchers randomized 1713 SCAS patients from 50 international centers to receive a 1: 1 stent placement (n = 855) or endarterectomy group (n = 858). The researchers completed the treatment analysis and intention-to-treat analysis (ITT) of 1,710 patients who completed the final 31 days of treatment. The main endpoint of fatal or disabling stroke occurred after randomization. Follow-up 4.2 years. Studies have shown that the stent-graft group and the endarterectomy group were lethal