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目的:探讨美托洛尔治疗老年慢性心力衰竭临床效果与安全性.方法:选取2011年7月至2013年5月住院治疗的老年慢性心力衰竭患者75例,入院后均给予卧床休息、低盐饮食、强心、利尿剂、血管紧张素转换酶抑制剂等常规抗心力衰竭治疗,并加用美托洛尔,初始剂量6.25mg,观察血压、心率和心力衰竭的症状和体征2~4h,若无不良反应,即口服6.25mg、2次/d、持续应用1~2周,无明显不良反应者加量为12.5mg、2次/d、直至25mg、2次/d.总结分析治疗后临床疗效.结果:治疗后总有效率90.67%,其中有5例患者出现头昏、心动过缓,经调整剂量后并未影响继续用药;治疗后收缩压和心率均低于治疗前(P<0.05),左室舒张末期内径小于治疗前(P<0.05),左室射血分数高于治疗前(P<0.05).结论:美托洛尔治疗老年慢性心力衰竭安全有效.“,”Objective:To investigate the clinical efficacy and safety of metoprolol in the treatment of elderly patients with chronic heart failure.Methods:from July 2011 to May 2013 75 cases of hospitalized elderly patients with chronic heart failure treatment,after admission were treated with bed rest,low salt diet,cardiotonic,diuretics,angiotensin converting enzyme inhibitors and other conventional anti heart failure treatment,combined with metoprolol,the initial dose of 6.25mg,blood pressure,heart rate and heart failure symptoms and signs 2~4h,if no adverse reaction,namely oral 6.25mg,2/d,after 1~2 weeks,no obvious adverse reaction was 12.5mg,2/d,2/d,up to 25mg.Summary and analysis of clinical efficacy after treatment.Results:after treatment,the total efficiency of 90.67%,of which 5 cases of patients with dizziness,bradycardia,adjusted dose did not affect the continued medication;after treatment,systolic blood pressure and heart rate were lower than those before treatment (P<0.05),left ventricular end diastolic diameter less than before treatment (P<0.05),left ventricular ejection scores higher than those before treatment (P<0.05).Conclusion:metoprolol is effective and safe in the treatment of elderly patients with chronic heart failure