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作者报告了急性肾功衰竭(ARF)时红细胞生成素(EPO)的水平。连续测定了5例少尿期ARF患者的EPO浓度,EPO明显低于正常,尤其在少尿期开始的2—3日内迅速下降,其中2例分别为挤压综合征(男21岁)和革兰氏染色阴性杆菌败血癌(女67岁)所引起的急性肾功衰竭,二者均透析治疗。例1,少尿期,随着血肌酐从370±mμol/L骤急上升到800μmol/L,EPO由35mlu/ml急剧下降至15±mlu/ml,Hb由12g/dl下降到8.5g/dl,一月后当血肌酐恢复正常后,EPO缓慢上升,Hb浓度亦逐渐提高。例2,少尿期,当血肌酐由
The authors report the level of erythropoietin (EPO) in acute renal failure (ARF). EPO concentrations in 5 oliguric ARF patients were determined continuously, EPO was significantly lower than normal, especially in 2-3 days after the beginning of oliguria, including 2 cases of crush syndrome (male 21 years old) and leather Acute renal failure caused by Langer-negative bacilli (67 years old), both dialysis. Example 1 In the oliguric phase, the EPO dropped sharply from 35 to 35 ± 1 μg / ml and serum Hb decreased from 12 to 8.5 g / dl with a rapid increase of serum creatinine from 370 ± mμol / L to 800 μmol / L After January, when serum creatinine returned to normal, EPO increased slowly and Hb concentration gradually increased. Example 2, oliguria, when the serum creatinine by