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[目的]建立数学模型预测和发现淋巴结转移的高危人群。[方法]回顾性分析1990年1月至1999年12月施行根治性切除的1051例大肠癌,并建立预测淋巴结转移的数学模型。[结果]预测大肠癌淋巴结转移的数学模型:淋巴结转移=-2.248-0.017×年龄-0.671×家族史+0.437×部位+0.508×病理分级+0.395×浸润深度。[结论]利用临床病理学参数建立的数学模型可以预测和发现有淋巴结转移倾向的高危人群。
[Objective] To establish a mathematical model to predict and identify high-risk patients with lymph node metastasis. [Methods] A retrospective analysis of 1051 cases of colorectal cancer undergoing radical resection from January 1990 to December 1999 was performed. A mathematical model for predicting lymph node metastasis was established. [Results] The mathematical model predicting lymph node metastasis of colorectal cancer: lymph node metastasis = -2.248-0.017 × age -0.671 × family history + 0.437 × site + 0.508 × pathological grade + 0.395 × depth of invasion. [Conclusion] The mathematical model established by clinicopathological parameters can predict and find high-risk groups with lymph node metastasis tendency.