【摘 要】
：
Objective To investigate the association of ghrelin gene polymorphisms with metabolic syndrome in Han Nationality Chinese. Methods A total of 240 patients with
【机 构】
：
Department of Endocrinology,National Laboratory of Medical Molecular Biology
论文部分内容阅读
Objective To investigate the association of ghrelin gene polymorphisms with metabolic syndrome in Han Nationality Chinese. Methods A total of 240 patients with metabolic syndrome annd 427 adults aged above forty years were recruited. Genotypes were determined by polymerase chain reaction and restriction fragment lengthpolymorphism analysis.Results The allelic frequency of the Leu72Met polymorphismwas 17.3% in the patient group and 11.9% in the control group(x2=7.36, P=0.007). Metabolic syndrome was more prevalent among carriers of the Met72 variant (43.8 vs 33.1%, age- and sex-adjusted odds ratio=1.57, P=0.01). No Arg51Gln variants were found in our study subjects. Conclusion Rather than being associated with its individual components, Leu72Met polymorphism is associated with metabolic syndrome in the Han Nationality Chinese. Arg51Gln polymorphism is rare in the Hart Nationality Chinese.
其他文献
根据重庆维普资讯的和万方数据资源系统的提供的引证数据,以中药类代表性期刊、、、、、、等为例,对2003～2005年三年发表论文的总被引情况进行分析,并对其中高频被引论文的学
本文对教育经济学中个人教育投资明瑟收益率的估计方法进行了比较研究,特别是引入了部分线性回归模型对明瑟收益率进行估计的方法,并且通过广义似然比检验对常规明瑟模型中的
对2000～2006年《中国科技期刊研究》载文作者群进行统计和分析,从文献计量学角度,对载文量的时间分布、作者群的地域和所属单位分布、核心作者群的数量及论文作者的合著率进行
In order to provide anatomical basis for transoral approach (TOA) in dealing with the ventro lesions of craniocervical junction, and the design and application
为了了解我国眼科学术类期刊的整体水平,根据(CAJCCR)及2001～2005年的统计数据,统计我国13种眼科类学术期刊的影响因子、被引频次、h指数等指标,并对有关指标作初步分析.
To get a better understanding of user behavior towards online learning systems, the technology acceptance model (TAM) was extended to include an intrinsic motiv
对国际知名期刊 CARBON 的办刊理念、运作和发展进行了详细的介绍和分析。通过比较学习国外期刊的办刊经验,针对目前我国科技期刊中普遍存在的问题认真思考,提出了有利于我国
This article introduces one of South Asias most important border regions into academic discourse, namely, the Central Himalayan mountain rim separating India an
目的 观察和了解原发性干燥综合征(pSS)患者发生恶性淋巴瘤(ML)的特点,探讨危险因素.方法 1980年1月至2010年8月在北京协和医院住院的pSS合并ML的患者(pSS/ML)共17例,进行回顾性分析;同期未合并ML的pSS患者(pSS/nML)共4485例,随机抽取163例进行比较.结果 (1)17例pSS/ML患者中女14例,男3例;平均年龄(53±13)岁,自发病至确诊pSS(8±9)
Based on the mathematical model of a novel cosine gear drive, a few characteristics, such as the contact ratio, the sliding coefficient, and the contact and ben