论文部分内容阅读
[目的]观察腺苷蛋氨酸联合异甘草酸镁治疗瘀胆型肝炎的疗效。[方法]90例患者随机分为2组各45例,治疗组采用腺苷蛋氨酸冻干粉针剂1 000 mg加入5%葡萄糖250 ml静脉滴注,1次/d,异甘草酸镁注射液100mg加入10%葡萄糖250 ml静脉滴注,1次/d;对照组采用苦黄注射液30 ml加入10%葡萄糖250 ml静脉滴注,1次/d,甘草酸二铵注射液150 mg加入10%葡萄糖250 ml静脉滴注,1次/d,疗程均为4周。观察患者治疗前后的症状和肝功能变化,并记录治疗过程中的不良反应。[结果]治疗组总有效率95.6%,优于对照组77.8%,2组比较差异有统计学意义(P<0.05)。治疗组治疗后肝功能指标均较治疗前改善(P<0.05),且各指标改善情况均优于对照组(P<0.05)。[结论]腺苷蛋氨酸联合异甘草酸镁治疗瘀胆型肝炎临床疗效明显。
[Objective] To observe the effect of adenosine methionine combined with magnesium isoglycyrrhizinate in the treatment of stasis gallstone hepatitis. [Method] 90 patients were randomly divided into two groups of 45 cases. The treatment group was treated with adenosine methionine lyophilized powder injection 1000 mg intravenously with 250 ml of 5% glucose once a day, 100 mg magnesium isoglycyrrhizinate injection added 10% Glucose 250 ml intravenous infusion, once / d; control group with Kuhuang injection 30 ml added 10% glucose 250 ml intravenous infusion, 1 / d, 150 mg of glycyrrhizic acid injection of 10% glucose 250 ml Intravenous infusion, 1 time / d, treatment are 4 weeks. Observed before and after treatment of patients with symptoms and liver function changes, and record the adverse reactions in the course of treatment. [Results] The total effective rate was 95.6% in the treatment group, which was better than 77.8% in the control group. There was significant difference between the two groups (P <0.05). The indexes of liver function in treatment group were better than before treatment (P <0.05), and the improvement of each index was better than that of control group (P <0.05). [Conclusion] Adenosine methionine combined with magnesium isoglycyrrhizinate has obvious curative effect on stasis.