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目的 探讨婴儿脑性瘫痪的病因及防治方法。方法 对 1998年 4月至 2 0 0 0年 6月确诊的 12 8例婴儿脑性瘫痪患儿分为干预组 30例 ,未系统干预组 35例 ,门诊转诊的 6 3例为对照组。 3组其性别、胎龄、出生体重、病情程度经统计学检验均无显著性差异 ,采用体格发育、神经系统检查及中国儿童智能发育量表评定发育商。结果 ①发病原因依次为缺氧缺血性脑病 (HIE) 72例 (5 6 .2 % )及颅内出血 (ICH) 12例 (9.3 % ) ,高胆红素血症 (高胆血症 ) 32例 (2 5 % ) ,感染 7例 (6 .5 % ) ,早产儿 5例 (3.9% )。②干预组的体重、头围明显大于未系统干预组及对照组。③干预、未系统干预及对照 3组智力发育指数 (MDI)各为 (75 .6± 12 .7) ,(38.4± 13.8) ,(4 9.7± 13.6 ) ,(P<0 .0 1) ;精神运动发育指数 (PDI)各为 (83 .3± 15 .3) ,(4 0 .6± 17.6 ) ,(5 1.4± 14.4) ,(P <0 .0 1) ,干预组明显高于未系统干预及对照组。结论 防治的重点应是预防及治疗HIE ,ICH ,高胆血症 ,感染及早产。早期干预和新生儿期后治疗以及水疗指针疗法的综合干预可以改善婴儿脑瘫的预后
Objective To investigate the etiology and prevention of cerebral palsy in infants. Methods A total of 128 infants with cerebral palsy diagnosed from April 1998 to June 2000 were divided into intervention group (n = 30), non-systemic intervention group (n = 35) and outpatient referral (n = 63) as control group. There were no significant differences in sex, gestational age, birth weight and severity of illness among the three groups by statistical test. Developmental traders were evaluated by physical development, neurological examination and Chinese children’s mental development scale. Results ① The causes were as follows: 72 cases (56.2%) with hypoxic-ischemic encephalopathy (HIE), 12 cases (9.3%) with intracranial hemorrhage (ICH), 32 cases with hyperbilirubinemia Cases (2.5%), infection in 7 cases (6.5%) and preterm infants in 5 cases (3.9%). ② The body weight and head circumference of intervention group were significantly larger than those of non-intervention group and control group. (3) The mental development index (MDI) in intervention group, control group and control group were (75.6 ± 12.7), (38.4 ± 13.8), (4.97 ± 13.6), (P <0.01) respectively; The indexes of psychomotor development index (PDI) were (83.3 ± 15.3), (40.6 ± 17.6) and (5.41 ± 14.4), respectively (P <0.01) System intervention and control group. Conclusion The prevention and treatment should focus on the prevention and treatment of HIE, ICH, hypercholemia, infection and premature delivery. Comprehensive interventions for early intervention and post-neonatal treatment and hydrotherapy may improve the prognosis of infant with cerebral palsy