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褪黑素（melatonin，MT）是松果体分泌的一种激素，对机体有广泛的影响。近几年的研究发现MT具有很强的自由基清除作用及抗氧化作用，且生物利用度高，极易通过血脑屏障和细胞膜，毒性低[1]，这使它避免了一些抗氧化剂的缺点。本实验观察了 MT对脑缺血再灌注沙土鼠脑组织SOD活性及MDA含量的影响。
Melatonin (MT) is a hormone secreted by the pineal gland and has a wide range of effects on the body. In recent years, studies have found that MT has a strong free radical scavenging effect and anti-oxidation, and high bioavailability, easily through the blood-brain barrier and cell membrane, low toxicity [1], which makes it avoid some of the antioxidant Disadvantages. The experiment observed MT on cerebral ischemia reperfusion in gerbil SOD activity and MDA content.