论文部分内容阅读
[研究背景 ]探讨肝炎后肝硬变患者血清胆汁酸与其他肝功能指标的关系及对肝硬变预后的价值 .[病列报告 ]测定 117例肝炎后肝硬变患者空腹血清胆汁酸 .血清胆汁酸的敏感性优于其他肝功能指标 ,但与总胆红素、谷草转氨酶之间无显著差异 ,与谷丙转氨酶、γ 谷氨酰转肽酶、碱性磷酸酶、直接胆红素之间无相关关系 .血清胆汁酸随肝功能Child Pugh分级的升高而逐渐升高 ,并发现血清胆汁酸低于5 0 μmol/L者 1年内死亡率为 7% ,而高于 5 0 μmol/L者 ,1年内死亡率为 5 5 % .[讨论 ]空腹血清胆汁酸在肝硬变的不同阶段都升高 ,即使是晚期肝硬变患者中亦如此 .血清胆汁酸能反映肝硬变的预后
[Background] To investigate the relationship between serum bile acids and other liver function indexes in patients with posthepatitic cirrhosis and their prognostic value in cirrhosis.Methods 117 patients with posthepatitic cirrhosis were tested for fasting serum bile acid Bile acid sensitivity is superior to other indicators of liver function, but with total bilirubin, aspartate aminotransferase no significant difference between, and alanine aminotransferase, gamma glutamyl transpeptidase, alkaline phosphatase, direct bilirubin There was no relationship between serum bile acid and Child Pugh grade liver function gradually increased and found that serum bile acid less than 50 μmol / L within 1 year mortality was 7%, while higher than 50 μmol / L, with a 1-year mortality rate of 55%. [Discussion] Fasting serum bile acids are elevated at different stages of cirrhosis, even in patients with advanced cirrhosis. Serum bile acids can reflect cirrhosis Prognosis