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目的:了解新生儿真菌血症的临床特征,为有效治疗及预防提供科学依据。方法:采用回顾性调查方法,对新生儿病房2007年发生真菌血症患儿的临床资料进行调查。结果:早产儿、极低体重儿、长时间使用抗生素、静脉营养是新生儿发生真菌血症的高危因素,引起感染的真菌主要为白色念珠菌及近平滑念珠菌两种,对氟康唑均敏感。结论:真菌血症是当前新生儿科所面临的一个严重问题,应针对高危因素采取相应的防治措施。
Objective: To understand the clinical features of neonatal fungemia and provide a scientific basis for effective treatment and prevention. Methods: A retrospective survey was conducted to investigate the clinical data of neonates with fungal sepsis in 2007 in neonatal wards. Results: Preterm infants, very low birth weight infants, prolonged use of antibiotics, intravenous nutrition is a neonatal risk of fungal exacerbation, the main fungal infections caused by Candida albicans and Candida parapsilosis are two, both fluconazole sensitive. Conclusions: Fungal bacteremia is a serious problem currently faced by neonatology. Corresponding prevention and treatment measures should be taken to deal with the risk factors.