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目的观察普芦卡必利对社区老年妇女功能性便秘的临床疗效,为指导临床用药提供依据。方法选择本院2013年3月-2014年9月消化科门诊老年妇女功能性便秘患者145例,分为3组,治疗组采用以普芦卡必利片进行治疗,对照组分为两组,一组仅用开塞露直接予以纳肛通便,另一组以乳果糖进行治疗,3组均以2周为一个疗程并随访2周。使用Bristol粪便量表记录患者便型进行评分,记录自发排便次数(SCBM)并观察不良反应发生情况。结果经过2周随访,治疗组粪便性状评分显著高于两组对照组,差异具有统计学意义(P<0.05,P<0.01)。治疗有效率为84.0%,显著高于两组对照组的66.0%和62.5%(P<0.05)。结论普芦卡必利片治疗社区老年妇女功能性便秘疗效好,且安全性良好。
Objective To observe the clinical efficacy of presuridine for functional constipation in community elderly women and provide the basis for guiding clinical medication. Methods A total of 145 elderly patients with functional constipation in our department from March 2013 to September 2014 were selected and divided into three groups. The treatment group was treated with propafar tablets, and the control group was divided into two groups. A group of only open cassia directly to accept anal laxative, the other group to lactulose treatment, three groups were 2 weeks for a course of treatment and follow-up of 2 weeks. The patients were scored on the Bristol fecal scale and the number of spontaneous bowel movements (SCBM) was recorded and the incidence of adverse reactions was observed. Results After 2 weeks of follow-up, the stool score of the treatment group was significantly higher than that of the control group (P <0.05, P <0.01). The effective rate of treatment was 84.0%, which was significantly higher than 66.0% and 62.5% of the two control groups (P <0.05). Conclusion The effect of propafasil tablet in the treatment of functional constipation in community elderly women is good and the safety is good.